Machine De Raffinage D or Aqua Regia China - it-events Machine De Raffinage D or Aqua Regia China Alchemy - cool blog Alchemy was practiced in Mesopotamia, Ancient Egypt, Persia, India, Japan, Korea and China, in Classical Greece and Rome, in the Muslim civilizations, and then in Europe up to the 19th century in a complex network of schools and philosophical systems spanning at least 2,500 years.